Pathophysiology of Castration-Resistant Prostate Cancer
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چکیده
Abbreviations CRPC Castration resistant prostate cancer PSA Prostate specific antigen ADT Androgen deprivation therapy DHT Dihydrotestosterone AR Androgen receptor DHEA Dehydroepiandrosterone AD Androstenedione HSP Heat shock protein IAP Inhibitors of apoptosis proteins PTEN Phosphatase and tensin homolog BTG1 B-Cell translocation gene 1 BCL2 B-Cell CLL/Lymphoma 2 IGF-1 Insulin like growth factor 1 KGF Keratinocyte growth factor EGF1 Epidermal growth factor 1 TIF2 Transcriptional intermediary factor 2 RTK Receptor tyrosine kinase MAPK Mitogen activated protein kinase STAT Signal transducer and activator of transcription AF-1, 2 Activating function NTD N-terminal domain
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تاریخ انتشار 2017